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MOTS-c pen, black
MOTS-c pen, pink

Energy & metabolism

MOTS-c

Energy and metabolism, from inside the cell

Format

Add a refill for your pen

MOTS-c 40 mg · +AED 1135 each

0

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1

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PriceAED 1180

Frequently paired with

Tap Add — each one counts toward your bundle saving.

NAD+ 500 mg

AED 880

RTTA 10 mg

AED 630

Also in a bundle: Metabolic pair · Energy & longevity

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Pens are added as the reusable pen; change the format on the product page if you prefer.

A mitochondrial-derived peptide that activates the AMPK pathway — the same energy-sensing route engaged by exercise and fasting. Studied in metabolism, endurance and fuel-use research.

Research use only. Supplied for laboratory and analytical research. Not a medicine or supplement, and not for human or animal use. We don't give dosing or clinical advice. Read the terms

Presentation
Lyophilised powder, reconstituted — 3 mL pen

Manufactured under controlled research-grade conditions. For documentation or questions about this compound, contact us on WhatsApp.

Published research

  1. Animal study

    In young, middle-aged and old mice, MOTS-c improved physical performance; separately, exercise raised natural MOTS-c levels in human muscle and blood.

    Reynolds JC, et al. MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis. Nature Communications. 2021. PMID 33473109

  2. Animal study

    In mice and cultured cells, MOTS-c acted mainly on skeletal muscle through AMPK activation and prevented diet-induced obesity and insulin resistance.

    Lee C, et al. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metabolism. 2015. PMID 25738459

  3. Review

    This short review describes MOTS-c as a peptide encoded by mitochondrial DNA that has been shown to act on skeletal muscle and enhance glucose metabolism, with possible relevance to obesity, diabetes, exercise and longevity.

    Lee C, et al. MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism. Free Radical Biology & Medicine. 2016. PMID 27216708

Short summaries of published studies, with links to the original papers. Results in animals or cells may not apply to people. This is not medical advice and not a guide to use.

All research on MOTS-c